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Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants

Tau is hyperphosphorylated in the brains of patients with tauopathies, such as Alzheimer’s disease and frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). However, neither the mechanism of hyperphosphorylation nor its contribution to pathogenesis is known. We applied Phos-tag...

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Detalles Bibliográficos
Autores principales:	Kimura, Taeko, Hosokawa, Tomohisa, Taoka, Masato, Tsutsumi, Koji, Ando, Kanae, Ishiguro, Koichi, Hosokawa, Masato, Hasegawa, Masato, Hisanaga, Shin-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027580/ https://www.ncbi.nlm.nih.gov/pubmed/27641626 http://dx.doi.org/10.1038/srep33479

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