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Lack of adrenomedullin in mouse endothelial cells results in defective angiogenesis, enhanced vascular permeability, less metastasis, and more brain damage

Adrenomedullin (AM) is a vasodilating peptide involved in the regulation of circulatory homeostasis and in the pathophysiology of certain cardiovascular diseases. AM plays critical roles in blood vessels, including regulation of vascular stability and permeability. To elucidate the autocrine/paracri...

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Detalles Bibliográficos
Autores principales: Ochoa-Callejero, Laura, Pozo-Rodrigálvarez, Andrea, Martínez-Murillo, Ricardo, Martínez, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027589/
https://www.ncbi.nlm.nih.gov/pubmed/27640364
http://dx.doi.org/10.1038/srep33495