Complement component 3 deficiency prolongs MHC-II disparate skin allograft survival by increasing the CD4(+) CD25(+) regulatory T cells population

Recent reports suggest that complement system contributes to allograft rejection. However, its underlying mechanism is poorly understood. Herein, we investigate the role of complement component 3 (C3) in a single MHC-II molecule mismatched murine model of allograft rejection using C3 deficient mice...

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Detalles Bibliográficos
Autores principales: Zheng, Quan-you, Liang, Shen-ju, Li, Gui-qing, Lv, Yan-bo, Li, You, Tang, Ming, Zhang, Kun, Xu, Gui-lian, Zhang, Ke-qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027598/
https://www.ncbi.nlm.nih.gov/pubmed/27641978
http://dx.doi.org/10.1038/srep33489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027598/
https://www.ncbi.nlm.nih.gov/pubmed/27641978
http://dx.doi.org/10.1038/srep33489

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