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Metastatic progression is associated with dynamic changes in the local microenvironment

Most cancer-associated deaths result from metastasis. However, it remains unknown whether the size, microenvironment or other features of a metastatic lesion dictate its behaviour or determine the efficacy of chemotherapy in the adjuvant (micrometastatic) setting. Here we delineate the natural histo...

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Detalles Bibliográficos
Autores principales: Aiello, Nicole M., Bajor, David L., Norgard, Robert J., Sahmoud, Amine, Bhagwat, Neha, Pham, Minh N., Cornish, Toby C., Iacobuzio-Donahue, Christine A., Vonderheide, Robert H., Stanger, Ben Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027614/
https://www.ncbi.nlm.nih.gov/pubmed/27628423
http://dx.doi.org/10.1038/ncomms12819