Cargando…
Metastatic progression is associated with dynamic changes in the local microenvironment
Most cancer-associated deaths result from metastasis. However, it remains unknown whether the size, microenvironment or other features of a metastatic lesion dictate its behaviour or determine the efficacy of chemotherapy in the adjuvant (micrometastatic) setting. Here we delineate the natural histo...
Autores principales: | Aiello, Nicole M., Bajor, David L., Norgard, Robert J., Sahmoud, Amine, Bhagwat, Neha, Pham, Minh N., Cornish, Toby C., Iacobuzio-Donahue, Christine A., Vonderheide, Robert H., Stanger, Ben Z. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027614/ https://www.ncbi.nlm.nih.gov/pubmed/27628423 http://dx.doi.org/10.1038/ncomms12819 |
Ejemplares similares
-
Echoes of the embryo: using the developmental biology toolkit to study cancer
por: Aiello, Nicole M., et al.
Publicado: (2016) -
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy
por: Kim, Il-Kyu, et al.
Publicado: (2023) -
MYC Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma
por: Maddipati, Ravikanth, et al.
Publicado: (2022) -
A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling
por: Nguyen, Duc-Huy T., et al.
Publicado: (2019) -
Pharmacologic Activation of the G Protein–Coupled Estrogen Receptor Inhibits Pancreatic Ductal Adenocarcinoma
por: Natale, Christopher A., et al.
Publicado: (2020)