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Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival

In solid tumours millions of cells are shed into the blood circulation each day. Only a subset of these circulating tumour cells (CTCs) survive, many of them presumable because of their potential to form multi-cellular clusters also named spheroids. Tumour cells within these spheroids are protected...

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Detalles Bibliográficos
Autores principales: Braunholz, Diana, Saki, Mohammad, Niehr, Franziska, Öztürk, Merve, Borràs Puértolas, Berta, Konschak, Robert, Budach, Volker, Tinhofer, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028019/
https://www.ncbi.nlm.nih.gov/pubmed/27643613
http://dx.doi.org/10.1371/journal.pone.0163149