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Linkage between Fitness of Yeast Cells and Adenylate Kinase Catalysis

Enzymes have evolved with highly specific values of their catalytic parameters k(cat) and K(M). This poses fundamental biological questions about the selection pressures responsible for evolutionary tuning of these parameters. Here we are address these questions for the enzyme adenylate kinase (Adk)...

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Detalles Bibliográficos
Autores principales: Tükenmez, Hasan, Magnussen, Helge Magnus, Kovermann, Michael, Byström, Anders, Wolf-Watz, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028032/
https://www.ncbi.nlm.nih.gov/pubmed/27642758
http://dx.doi.org/10.1371/journal.pone.0163115