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Sonidegib, a novel smoothened inhibitor for the treatment of advanced basal cell carcinoma

Basal cell carcinoma (BCC) is the most common nonmelanoma skin cancer. If left untreated, BCCs can become locally aggressive or even metastasize. Currently available treatments include local destruction, surgery, and radiation. Systemic options for advanced disease are limited. The Hedgehog (Hh) pat...

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Detalles Bibliográficos
Autores principales: Doan, Hung Q, Silapunt, Sirunya, Migden, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028081/
https://www.ncbi.nlm.nih.gov/pubmed/27695345
http://dx.doi.org/10.2147/OTT.S108171