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Dual-function synthetic peptide derived from BMP4 for highly efficient tumor targeting and antiangiogenesis

Angiogenesis plays a critical role in the growth and metastasis of cancer, and growth factors released from cancer promote blood-vessel formation in the tumor microenvironment. The angiogenesis is accelerated via interactions of growth factors with the high-affinity receptors on cancer cells. In par...

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Detalles Bibliográficos
Autores principales: Choi, Suk Hyun, Lee, Jue Yeon, Suh, Jin Sook, Park, Yoon Shin, Chung, Chong Pyoung, Park, Yoon Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028098/
https://www.ncbi.nlm.nih.gov/pubmed/27695323
http://dx.doi.org/10.2147/IJN.S115044