Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-Immune Adults: A Phase 1, Double-Blinded Placebo Controlled Dosage Escalation Study

The erythrocyte binding antigen region II (EBA-175 RII) is a Plasmodium falciparum ligand that mediates erythrocyte invasion and is considered an important malaria vaccine candidate. A phase Ia trial in malaria naïve adults living in the United States found the recombinant non-glycosylated vaccine a...

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Detalles Bibliográficos
Autores principales: Koram, Kwadwo A., Adu, Bright, Ocran, Josephine, Karikari, Yaa S., Adu-Amankwah, Susan, Ntiri, Michael, Abuaku, Benjamin, Dodoo, Daniel, Gyan, Ben, Kronmann, Karl C., Nkrumah, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028127/
https://www.ncbi.nlm.nih.gov/pubmed/27644034
http://dx.doi.org/10.1371/journal.pone.0163066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028127/
https://www.ncbi.nlm.nih.gov/pubmed/27644034
http://dx.doi.org/10.1371/journal.pone.0163066

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