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The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice

Cortical expansion and folding are often linked to the evolution of higher intelligence, but molecular and cellular mechanisms underlying cortical folding remain poorly understood. The hominoid-specific gene TBC1D3 undergoes segmental duplications during hominoid evolution, but its role in brain dev...

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Detalles Bibliográficos
Autores principales: Ju, Xiang-Chun, Hou, Qiong-Qiong, Sheng, Ai-Li, Wu, Kong-Yan, Zhou, Yang, Jin, Ying, Wen, Tieqiao, Yang, Zhengang, Wang, Xiaoqun, Luo, Zhen-Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028191/
https://www.ncbi.nlm.nih.gov/pubmed/27504805
http://dx.doi.org/10.7554/eLife.18197