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ENHANCING ADULT NERVE REGENERATION THROUGH THE KNOCKDOWN OF RETINOBLASTOMA PROTEIN

Tumour suppressor pathways may offer novel targets capable of altering the plasticity of post-mitotic adult neurons. Here we describe a role for retinoblastoma (Rb) protein, widely expressed in adult sensory neurons and their axons, during regeneration. In adult sensory neurons, Rb siRNA knockdown o...

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Detalles Bibliográficos
Autores principales: Christie, Kimberly J., Krishnan, Anand, Martinez, Jose A., Purdy, Kaylynn, Singh, Bhagat, Eaton, Shane, Zochodne, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028199/
https://www.ncbi.nlm.nih.gov/pubmed/24752312
http://dx.doi.org/10.1038/ncomms4670