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Mechanistic Insights into Cofactor-Dependent Coupling of RNA Folding and mRNA Transcription/Translation by a Cobalamin Riboswitch

Riboswitches are mRNA elements regulating gene expression in response to direct binding of a metabolite. While these RNAs are increasingly well understood with respect to interactions between receptor domains and their cognate effector molecules, little is known about the specific mechanistic relati...

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Detalles Bibliográficos
Autores principales: Polaski, Jacob T., Holmstrom, Erik D., Nesbitt, David J., Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028336/
https://www.ncbi.nlm.nih.gov/pubmed/27117410
http://dx.doi.org/10.1016/j.celrep.2016.03.087