Synthesis of polybrominated benzimidazole and benzotriazole derivatives containing a tetrazole ring and their cytotoxic activity

ABSTRACT: A series of new benzimidazole and benzotriazole derivatives containing a tetrazole moiety was synthesized by N-alkylation of 5-aryltetrazole with 4,5,6,7-tetrabromo-1-(3-chloropropyl)-1H-benzimidazole and 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-benzotriazole. The reaction was regioselecti...

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Detalles Bibliográficos
Autores principales: Łukowska-Chojnacka, Edyta, Wińska, Patrycja, Wielechowska, Monika, Bretner, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028404/
https://www.ncbi.nlm.nih.gov/pubmed/27729714
http://dx.doi.org/10.1007/s00706-016-1785-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028404/
https://www.ncbi.nlm.nih.gov/pubmed/27729714
http://dx.doi.org/10.1007/s00706-016-1785-8

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