Genome-Wide Anaplasma phagocytophilum AnkA-DNA Interactions Are Enriched in Intergenic Regions and Gene Promoters and Correlate with Infection-Induced Differential Gene Expression

Anaplasma phagocytophilum, an obligate intracellular prokaryote, infects neutrophils, and alters cardinal functions via reprogrammed transcription. Large contiguous regions of neutrophil chromosomes are differentially expressed during infection. Secreted A. phagocytophilum effector AnkA transits int...

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Detalles Bibliográficos
Autores principales: Dumler, J. Stephen, Sinclair, Sara H., Pappas-Brown, Valeria, Shetty, Amol C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028410/
https://www.ncbi.nlm.nih.gov/pubmed/27703927
http://dx.doi.org/10.3389/fcimb.2016.00097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028410/
https://www.ncbi.nlm.nih.gov/pubmed/27703927
http://dx.doi.org/10.3389/fcimb.2016.00097

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