Modulation of Phenotype and Function of Human CD4(+)CD25(+) T Regulatory Lymphocytes Mediated by cAMP-Elevating Agents

We have shown that cholera toxin (CT) and other cyclic AMP (cAMP)-elevating agents induce upregulation of the inhibitory molecule CTLA-4 in human resting CD4(+) T lymphocytes, which following the treatment acquired suppressive functions. In this study, we evaluated the effect of cAMP-elevating agent...

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Detalles Bibliográficos
Autores principales: Riccomi, Antonella, Gesa, Valentina, Sacchi, Alessandra, De Magistris, Maria Teresa, Vendetti, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028705/
https://www.ncbi.nlm.nih.gov/pubmed/27703455
http://dx.doi.org/10.3389/fimmu.2016.00358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028705/
https://www.ncbi.nlm.nih.gov/pubmed/27703455
http://dx.doi.org/10.3389/fimmu.2016.00358

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