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Modulation of Phenotype and Function of Human CD4(+)CD25(+) T Regulatory Lymphocytes Mediated by cAMP-Elevating Agents
We have shown that cholera toxin (CT) and other cyclic AMP (cAMP)-elevating agents induce upregulation of the inhibitory molecule CTLA-4 in human resting CD4(+) T lymphocytes, which following the treatment acquired suppressive functions. In this study, we evaluated the effect of cAMP-elevating agent...
Autores principales: | Riccomi, Antonella, Gesa, Valentina, Sacchi, Alessandra, De Magistris, Maria Teresa, Vendetti, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028705/ https://www.ncbi.nlm.nih.gov/pubmed/27703455 http://dx.doi.org/10.3389/fimmu.2016.00358 |
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