Adenovirus-mediated expression of orphan nuclear receptor NR4A2 targeting hepatic stellate cell attenuates liver fibrosis in rats

Liver fibrosis is a wound-healing response characterized with the accumulation of extracellular matrix (ECM). And hepatic stellate cells (HSCs) are the principal cell source of ECM. NR4A2 (Nurr1) is a member of orphan nuclear receptor NR4A family and acts as transcription factor. It participates in...

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Detalles Bibliográficos
Autores principales: Chen, Pengguo, Li, Jie, Huo, Yan, Lu, Jin, Wan, Lili, Yang, Quanjun, Huang, Jinlu, Gan, Run, Guo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028713/
https://www.ncbi.nlm.nih.gov/pubmed/27646469
http://dx.doi.org/10.1038/srep33593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028713/
https://www.ncbi.nlm.nih.gov/pubmed/27646469
http://dx.doi.org/10.1038/srep33593

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