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Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro
Iron importer divalent metal transporter 1 (DMT1) plays a crucial role in the nigal iron accumulation in Parkinson’s disease (PD). Membrane hyperpolarization is one of the factors that could affect its iron transport function. Besides iron, selective activation of the ATP-sensitive potassium (K(ATP)...
Autores principales: | Du, Xixun, Xu, Huamin, Shi, Limin, Jiang, Zhifeng, Song, Ning, Jiang, Hong, Xie, Junxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028757/ https://www.ncbi.nlm.nih.gov/pubmed/27646472 http://dx.doi.org/10.1038/srep33674 |
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