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Enhanced release of primary signals may render intercellular signalling ineffective due to spatial aspects

Detailed mechanistic modelling has been performed of the intercellular signalling cascade between precancerous cells and their normal neighbours that leads to a selective removal of the precancerous cells by apoptosis. Two interconnected signalling pathways that were identified experimentally have b...

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Detalles Bibliográficos
Autores principales: Kundrát, Pavel, Friedland, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028836/
https://www.ncbi.nlm.nih.gov/pubmed/27645799
http://dx.doi.org/10.1038/srep33214