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Enhanced release of primary signals may render intercellular signalling ineffective due to spatial aspects
Detailed mechanistic modelling has been performed of the intercellular signalling cascade between precancerous cells and their normal neighbours that leads to a selective removal of the precancerous cells by apoptosis. Two interconnected signalling pathways that were identified experimentally have b...
Autores principales: | Kundrát, Pavel, Friedland, Werner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028836/ https://www.ncbi.nlm.nih.gov/pubmed/27645799 http://dx.doi.org/10.1038/srep33214 |
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