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Ablation of Y(1) receptor impairs osteoclast bone-resorbing activity

Y(1) receptor (Y(1)R)-signalling pathway plays a pivotal role in the regulation of bone metabolism. The lack of Y(1)R-signalling stimulates bone mass accretion that has been mainly attributed to Y(1)R disruption from bone-forming cells. Still, the involvement of Y(1)R-signalling in the control of bo...

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Detalles Bibliográficos
Autores principales: Sousa, Daniela M., Conceição, Francisco, Silva, Diana I., Leitão, Luís, Neto, Estrela, Alves, Cecília J., Alencastre, Inês S., Herzog, Herbert, Aguiar, Paulo, Lamghari, Meriem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028844/
https://www.ncbi.nlm.nih.gov/pubmed/27646989
http://dx.doi.org/10.1038/srep33470