HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism

Endothelial damage is a critical mediator of myocardial ischemia/reperfusion (I/R) injury. HSPA12B is an endothelial-cell-specifically expressed heat shock protein. However, the roles of HSPA12B in acute myocardial I/R injury is unknown. Here we reported that myocardial I/R upregulated HSPA12B expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Qiuyue, Dai, Leyang, Wang, Yana, Zhang, Xiaojin, Li, Chuanfu, Jiang, Surong, Li, Yuehua, Ding, Zhengnian, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028890/
https://www.ncbi.nlm.nih.gov/pubmed/27644317
http://dx.doi.org/10.1038/srep33636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028890/
https://www.ncbi.nlm.nih.gov/pubmed/27644317
http://dx.doi.org/10.1038/srep33636

Ejemplares similares