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Robo3A and Robo3B expression is regulated via alternative promoters and mRNA stability

BACKGROUND: The transmembrane receptor family Roundabout (Robo) was described to have an essential role in the developing nervous system. Recent studies demonstrated that Robo3 shows an altered expression in rheumatoid arthritis as well as in melanoma. CONTEXT AND PURPOSE OF THE STUDY: Until today n...

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Detalles Bibliográficos
Autores principales: Ruedel, Anke, Schott, Mandy, Schubert, Thomas, Bosserhoff, Anja Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028924/
https://www.ncbi.nlm.nih.gov/pubmed/27660555
http://dx.doi.org/10.1186/s12935-016-0347-9