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Exosomes/tricalcium phosphate combination scaffolds can enhance bone regeneration by activating the PI3K/Akt signaling pathway

BACKGROUND: Recently, accumulating evidence has shown that exosomes, the naturally secreted nanocarriers of cells, can exert therapeutic effects in various disease models in the absence of parent cells. However, application of exosomes in bone defect repair and regeneration has been rarely reported,...

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Detalles Bibliográficos
Autores principales: Zhang, Jieyuan, Liu, Xiaolin, Li, Haiyan, Chen, Chunyuan, Hu, Bin, Niu, Xin, Li, Qing, Zhao, Bizeng, Xie, Zongping, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028974/
https://www.ncbi.nlm.nih.gov/pubmed/27650895
http://dx.doi.org/10.1186/s13287-016-0391-3