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A case report of Grover’s disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1

BACKGROUND: Immune related adverse events (irAEs) are common side effects of checkpoint inhibitory (CPI) therapies targeting CTLA-4 and PD-1/PD-L1. Grover’s disease is an uncommon dermatologic condition with unclear pathogenesis previously reported as an irAE with ipilimumab. CASE PRESENTATION: We r...

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Detalles Bibliográficos
Autores principales: Uemura, Marc, Faisal, Faa’k, Haymaker, Cara, McQuail, Natalie, Sirmans, Elizabeth, Hudgens, Courtney W., Barbara, Lydia, Bernatchez, Chantale, Curry, Jonathan L., Hwu, Patrick, Tetzlaff, Michael T., Diab, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028978/
https://www.ncbi.nlm.nih.gov/pubmed/27660709
http://dx.doi.org/10.1186/s40425-016-0157-6