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SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas

BACKGROUND: Colorectal cancer (CRC) appear to arise from precursor lesions in a well-characterized adenoma-carcinoma sequence. Significant efforts have been invested to develop biomarkers that identify early adenocarcinomas and adenomas with high-grade dysplasia, since these are believed to harbor a...

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Detalles Bibliográficos
Autores principales: Semaan, Alexander, van Ellen, Anne, Meller, Sebastian, Bergheim, Dominik, Branchi, Vittorio, Lingohr, Philipp, Goltz, Diane, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno, Pantelis, Dimitrios, Dietrich, Dimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028994/
https://www.ncbi.nlm.nih.gov/pubmed/27660666
http://dx.doi.org/10.1186/s13148-016-0267-5