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Neonatal monocytes exhibit a unique histone modification landscape

BACKGROUND: Neonates have dampened expression of pro-inflammatory cytokines and difficulty clearing pathogens. This makes them uniquely susceptible to infections, but the factors regulating neonatal-specific immune responses are poorly understood. Epigenetics, including histone modifications, can ac...

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Detalles Bibliográficos
Autores principales: Bermick, Jennifer R., Lambrecht, Nathalie J., denDekker, Aaron D., Kunkel, Steven L., Lukacs, Nicholas W., Hogaboam, Cory M., Schaller, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028999/
https://www.ncbi.nlm.nih.gov/pubmed/27660665
http://dx.doi.org/10.1186/s13148-016-0265-7