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Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathy
Laminopathy is a disease closely related to deficiency of the nuclear matrix protein lamin A/C or failure in prelamin A processing, and leads to accumulation of the misfold protein causing progeria. The resultant disrupted lamin function is highly associated with abnormal nuclear architecture, cell...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029055/ https://www.ncbi.nlm.nih.gov/pubmed/27649756 http://dx.doi.org/10.1186/s13287-016-0401-5 |