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Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome

Cystic fibrosis (CF) lungs are filled with thick mucus that obstructs airways and facilitates chronic infections. Pseudomonas aeruginosa is a significant pathogen of this disease that produces a variety of toxic small molecules. We used molecular networking-based metabolomics to investigate the chem...

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Detalles Bibliográficos
Autores principales: Quinn, Robert A, Phelan, Vanessa V, Whiteson, Katrine L, Garg, Neha, Bailey, Barbara A, Lim, Yan Wei, Conrad, Douglas J, Dorrestein, Pieter C, Rohwer, Forest L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029181/
https://www.ncbi.nlm.nih.gov/pubmed/26623545
http://dx.doi.org/10.1038/ismej.2015.207