Gld2-catalyzed 3′ monoadenylation of miRNAs in the hippocampus has no detectable effect on their stability or on animal behavior

Gld2, a noncanonical cytoplasmic poly(A) polymerase, interacts with the RNA binding protein CPEB1 to mediate polyadenylation-induced translation in dendrites of cultured hippocampal neurons. Depletion of Gld2 from the hippocampus leads to a deficit in long-term potentiation evoked by theta burst sti...

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Detalles Bibliográficos
Autores principales: Mansur, Fernanda, Ivshina, Maria, Gu, Weifeng, Schaevitz, Laura, Stackpole, Emily, Gujja, Sharvari, Edwards, Yvonne J.K., Richter, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029448/
https://www.ncbi.nlm.nih.gov/pubmed/27495319
http://dx.doi.org/10.1261/rna.056937.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029448/
https://www.ncbi.nlm.nih.gov/pubmed/27495319
http://dx.doi.org/10.1261/rna.056937.116

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