Cargando…

Structure–function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation

In Eukarya and Archaea, in addition to protein-only pseudouridine (Ψ) synthases, complexes containing one guide RNA and four proteins can also produce Ψ. Cbf5 protein is the Ψ synthase in the complex. Previously, we showed that Ψ’s at positions 1940, 1942, and 2605 of Haloferax volcanii 23S rRNA are...

Descripción completa

Detalles Bibliográficos
Autores principales: Majumder, Mrinmoyee, Bosmeny, Michael S., Gupta, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029457/
https://www.ncbi.nlm.nih.gov/pubmed/27539785
http://dx.doi.org/10.1261/rna.057547.116