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Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogramming

Clonal level random allelic expression imbalance and random monoallelic expression provides cellular heterogeneity within tissues by modulating allelic dosage. Although such expression patterns have been observed in multiple cell types, little is known about when in development these stochastic alle...

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Detalles Bibliográficos
Autores principales: Jeffries, Aaron Richard, Uwanogho, Dafe Aghogho, Cocks, Graham, Perfect, Leo William, Dempster, Emma, Mill, Jonathan, Price, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029458/
https://www.ncbi.nlm.nih.gov/pubmed/27539784
http://dx.doi.org/10.1261/rna.058347.116