Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1(ΔE9) mice: potential mechanism underlying cognitive impairment

Senescence-accelerated mouse prone 8 strain (SAMP8) and PrP-hAβPPswe/PS1(ΔE9) (APP/PS1) mice are classic animal models of sporadic Alzheimer's disease and familial AD respectively. Our study showed that object recognition memory, spatial learning and memory, active and passive avoidance were de...

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Detalles Bibliográficos
Autores principales: Wang, Jian-hui, Cheng, Xiao-rui, Zhang, Xiao-rui, Wang, Tong-xing, Xu, Wen-jian, Li, Fei, Liu, Feng, Cheng, Jun-ping, Bo, Xiao-chen, Wang, Sheng-qi, Zhou, Wen-xia, Zhang, Yong-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029605/
https://www.ncbi.nlm.nih.gov/pubmed/27049828
http://dx.doi.org/10.18632/oncotarget.8453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029605/
https://www.ncbi.nlm.nih.gov/pubmed/27049828
http://dx.doi.org/10.18632/oncotarget.8453

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