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Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1(ΔE9) mice: potential mechanism underlying cognitive impairment
Senescence-accelerated mouse prone 8 strain (SAMP8) and PrP-hAβPPswe/PS1(ΔE9) (APP/PS1) mice are classic animal models of sporadic Alzheimer's disease and familial AD respectively. Our study showed that object recognition memory, spatial learning and memory, active and passive avoidance were de...
Autores principales: | Wang, Jian-hui, Cheng, Xiao-rui, Zhang, Xiao-rui, Wang, Tong-xing, Xu, Wen-jian, Li, Fei, Liu, Feng, Cheng, Jun-ping, Bo, Xiao-chen, Wang, Sheng-qi, Zhou, Wen-xia, Zhang, Yong-xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029605/ https://www.ncbi.nlm.nih.gov/pubmed/27049828 http://dx.doi.org/10.18632/oncotarget.8453 |
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