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Adipose triglyceride lipase decrement affects skeletal muscle homeostasis during aging through FAs-PPARα-PGC-1α antioxidant response

During aging skeletal muscle shows an accumulation of oxidative damage as well as intramyocellular lipid droplets (IMLDs). However, although the impact of these modifications on muscle tissue physiology is well established, the direct effectors critical for their occurrence are poorly understood. He...

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Detalles Bibliográficos
Autores principales: Aquilano, Katia, Baldelli, Sara, Barbera, Livia La, Barbato, Daniele Lettieri, Tatulli, Giuseppe, Ciriolo, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029607/
https://www.ncbi.nlm.nih.gov/pubmed/27056902
http://dx.doi.org/10.18632/oncotarget.8552