The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet β-cell hypertrophy and dysfunction

Heat shock protein 60 (HSP60) is a mitochondrial chaperone. Advanced glycation end products (AGEs) have been shown to interfere with the β-cell function. We hypothesized that AGEs induced β-cell hypertrophy and dysfunction through a HSP60 dysregulation pathway during the stage of islet/β-cell hypert...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Siao-Syun, Sheu, Meei-Ling, Yang, Rong-Sen, Chan, Ding-Cheng, Wu, Cheng-Tien, Yang, Ting-Hua, Chiang, Chih-Kang, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029611/
https://www.ncbi.nlm.nih.gov/pubmed/27056903
http://dx.doi.org/10.18632/oncotarget.8604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029611/
https://www.ncbi.nlm.nih.gov/pubmed/27056903
http://dx.doi.org/10.18632/oncotarget.8604

Ejemplares similares