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The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet β-cell hypertrophy and dysfunction

Heat shock protein 60 (HSP60) is a mitochondrial chaperone. Advanced glycation end products (AGEs) have been shown to interfere with the β-cell function. We hypothesized that AGEs induced β-cell hypertrophy and dysfunction through a HSP60 dysregulation pathway during the stage of islet/β-cell hypert...

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Detalles Bibliográficos
Autores principales:	Guan, Siao-Syun, Sheu, Meei-Ling, Yang, Rong-Sen, Chan, Ding-Cheng, Wu, Cheng-Tien, Yang, Ting-Hua, Chiang, Chih-Kang, Liu, Shing-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029611/ https://www.ncbi.nlm.nih.gov/pubmed/27056903 http://dx.doi.org/10.18632/oncotarget.8604

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