Hepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability

Hepatitis B virus (HBV) is a driver of hepatocellular carcinoma, and two viral products, X and large surface antigen (LHBS), are viral oncoproteins. During chronic viral infection, immune-escape mutants on the preS2 region of LHBS (preS2-LHBS) are gain-of-function mutations that are linked to preneo...

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Detalles Bibliográficos
Autores principales: Yen, Tim Ting-Chung, Yang, Anderson, Chiu, Wen-Tai, Li, Tian-Neng, Wang, Lyu-Han, Wu, Yi-Hsuan, Wang, Hui-Chen, Chen, Linyi, Wang, Wen-Ching, Huang, Wenya, Chang, Chien-Wen, Chang, Margaret Dah-Tsyr, Shen, Meng-Ru, Su, Ih-Jen, Wang, Lily Hui-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029631/
https://www.ncbi.nlm.nih.gov/pubmed/26992221
http://dx.doi.org/10.18632/oncotarget.8109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029631/
https://www.ncbi.nlm.nih.gov/pubmed/26992221
http://dx.doi.org/10.18632/oncotarget.8109

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