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Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis

PURPOSE: Cdc20 and c-Myc are commonly overexpressed in a broad spectrum of cancers, including glioblastoma (GBM). Despite this clear association, whether c-Myc and Cdc20 overexpression is a driver or passenger event in gliomagenesis remains unclear. RESULTS: Both c-Myc and Cdc20 induced the prolifer...

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Detalles Bibliográficos
Autores principales: Ji, Ping, Zhou, Xinhui, Liu, Qun, Fuller, Gregory N., Phillips, Lynette M., Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029644/
https://www.ncbi.nlm.nih.gov/pubmed/26993778
http://dx.doi.org/10.18632/oncotarget.8080