HER2-siRNA delivered by EGFR-specific single chain antibody inhibits NSCLC cell proliferation and tumor growth

Overexpression of human epidermal growth factor receptor type2 (HER2) is closely associated with aggressive progression and poor prognosis in non-small cell lung cancer (NSCLC). Here, we generated an EGFR-scFv-arginine nonamer peptide fusion protein (scFv-9R) as a cargo to deliver HER2 specific siRN...

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Detalles Bibliográficos
Autores principales: Lu, Yuan, Wang, Yuan, Zhang, Mi, Liu, Li, Li, Fakai, Zhang, Jian, Ye, Mingxiang, Zhao, Hu, Zhao, Jing, Yan, Bo, Yang, Angang, Zhang, Rui, Li, Xia, Ren, Xinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029650/
https://www.ncbi.nlm.nih.gov/pubmed/26988752
http://dx.doi.org/10.18632/oncotarget.8053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029650/
https://www.ncbi.nlm.nih.gov/pubmed/26988752
http://dx.doi.org/10.18632/oncotarget.8053

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