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Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition

E2F transcription factors are involved in cell cycle regulation and synthesis of DNA in mammalian cells, and simultaneously play important roles in the development and progression of cancer when dysregulated. E2F8, a novel identified E2F family member, was found to be associated with the progression...

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Detalles Bibliográficos
Autores principales: Ye, Liping, Guo, Ling, He, Zhenyu, Wang, Xi, Lin, Chuyong, Zhang, Xin, Wu, Shu, Bao, Yong, Yang, Qi, Song, Libing, Lin, Huanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029661/
https://www.ncbi.nlm.nih.gov/pubmed/26992224
http://dx.doi.org/10.18632/oncotarget.8121