PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells

Defects in ribosome biogenesis triggers a stress response (ribosomal stress) that can lead to growth arrest and apoptosis. Signaling pathways activated by ribosomal stress are specifically involved in the pathological mechanism of a group of disorders defined as ribosomopathies. However, more genera...

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Detalles Bibliográficos
Autores principales: Sagar, Vinay, Caldarola, Sara, Aria, Valentina, Monteleone, Valentina, Fuoco, Claudia, Gargioli, Cesare, Cannata, Stefano, Loreni, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029667/
https://www.ncbi.nlm.nih.gov/pubmed/26993775
http://dx.doi.org/10.18632/oncotarget.8070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029667/
https://www.ncbi.nlm.nih.gov/pubmed/26993775
http://dx.doi.org/10.18632/oncotarget.8070

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