Cargando…

PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells

Defects in ribosome biogenesis triggers a stress response (ribosomal stress) that can lead to growth arrest and apoptosis. Signaling pathways activated by ribosomal stress are specifically involved in the pathological mechanism of a group of disorders defined as ribosomopathies. However, more genera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sagar, Vinay, Caldarola, Sara, Aria, Valentina, Monteleone, Valentina, Fuoco, Claudia, Gargioli, Cesare, Cannata, Stefano, Loreni, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029667/ https://www.ncbi.nlm.nih.gov/pubmed/26993775 http://dx.doi.org/10.18632/oncotarget.8070

Ejemplares similares

Depletion of ribosomal protein S19 causes a reduction of rRNA synthesis
por: Juli, Giada, et al.
Publicado: (2016)

Matrix scaffolding for stem cell guidance toward skeletal muscle tissue engineering
por: Fuoco, Claudia, et al.
Publicado: (2016)

Ribosomal stress activates eEF2K–eEF2 pathway causing translation elongation inhibition and recruitment of Terminal Oligopyrimidine (TOP) mRNAs on polysomes
por: Gismondi, Angelo, et al.
Publicado: (2014)

Myoblast Myogenic Differentiation but Not Fusion Process Is Inhibited via MyoD Tetraplex Interaction
por: Testa, Stefano, et al.
Publicado: (2018)

The War after War: Volumetric Muscle Loss Incidence, Implication, Current Therapies and Emerging Reconstructive Strategies, a Comprehensive Review
por: Testa, Stefano, et al.
Publicado: (2021)

Metformin Protects Skeletal Muscle from Cardiotoxin Induced Degeneration
por: Langone, Francesca, et al.
Publicado: (2014)

Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo
por: Gargioli, Cesare, et al.
Publicado: (2018)

Skeletal Muscle-Derived Human Mesenchymal Stem Cells: Influence of Different Culture Conditions on Proliferative and Myogenic Capabilities
por: Testa, Stefano, et al.
Publicado: (2020)

Highly Permeable Matrimid(®)/PIM-EA(H(2))-TB Blend Membrane for Gas Separation
por: Esposito, Elisa, et al.
Publicado: (2018)

Characterization by mass cytometry of different methods for the preparation of muscle mononuclear cells
por: Spada, Filomena, et al.
Publicado: (2016)

A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
por: Reggio, Alessio, et al.
Publicado: (2023)

Injectable polyethylene glycol-fibrinogen hydrogel adjuvant improves survival and differentiation of transplanted mesoangioblasts in acute and chronic skeletal-muscle degeneration
por: Fuoco, Claudia, et al.
Publicado: (2012)

Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy
por: Aspesi, Anna, et al.
Publicado: (2017)

Author Correction: Lymphoblastoid cell lines from Diamond Blackfan anaemia patients exhibit a full ribosomal stress phenotype that is rescued by gene therapy
por: Aspesi, Anna, et al.
Publicado: (2018)

Regulation of myoblast differentiation by metabolic perturbations induced by metformin
por: Pavlidou, Theodora, et al.
Publicado: (2017)

In vivo restoration of dystrophin expression in mdx mice using intra-muscular and intra-arterial injections of hydrogel microsphere carriers of exon skipping antisense oligonucleotides
por: Cohen, Shani Attias, et al.
Publicado: (2022)

3D hydrogel environment rejuvenates aged pericytes for skeletal muscle tissue engineering
por: Fuoco, Claudia, et al.
Publicado: (2014)

Corrigendum: 3D hydrogel environment rejuvenates aged pericytes for skeletal muscle tissue engineering
por: Fuoco, Claudia, et al.
Publicado: (2019)

Thin Film Composite Membranes Based on the Polymer of Intrinsic Microporosity PIM-EA(Me(2))-TB Blended with Matrimid(®)5218
por: Longo, Mariagiulia, et al.
Publicado: (2022)

In vivo generation of a mature and functional artificial skeletal muscle
por: Fuoco, Claudia, et al.
Publicado: (2015)

Combined therapy with RAD001 e BEZ235 overcomes resistance of PET immortalized cell lines to mTOR inhibition
por: Passacantilli, Ilaria, et al.
Publicado: (2014)

Metformin Delays Satellite Cell Activation and Maintains Quiescence
por: Pavlidou, Theodora, et al.
Publicado: (2019)

Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP
por: Esposito, Davide, et al.
Publicado: (2014)

Engineering Muscle Networks in 3D Gelatin Methacryloyl Hydrogels: Influence of Mechanical Stiffness and Geometrical Confinement
por: Costantini, Marco, et al.
Publicado: (2017)

The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
por: Reggio, Alessio, et al.
Publicado: (2019)

Tröger’s Base Network Polymers of Intrinsic Microporosity (TB-PIMs) with Tunable Pore Size for Heterogeneous Catalysis
por: Antonangelo, Ariana R., et al.
Publicado: (2022)

Combination of biochemical and mechanical cues for tendon tissue engineering
por: Testa, Stefano, et al.
Publicado: (2017)

Synthesis and Transport Properties of Novel MOF/PIM-1/MOF Sandwich Membranes for Gas Separation
por: Fuoco, Alessio, et al.
Publicado: (2017)

High-Dimensional Single-Cell Quantitative Profiling of Skeletal Muscle Cell Population Dynamics during Regeneration
por: Petrilli, Lucia Lisa, et al.
Publicado: (2020)

Extracellular Vesicles from Skeletal Muscle Cells Efficiently Promote Myogenesis in Induced Pluripotent Stem Cells
por: Baci, Denisa, et al.
Publicado: (2020)

Biofabricating murine and human myo‐substitutes for rapid volumetric muscle loss restoration
por: Costantini, Marco, et al.
Publicado: (2021)

Long-term longitudinal study on swine VML model
por: De Paolis, Francesca, et al.
Publicado: (2023)

Reticulon-1C Involvement in Muscle Regeneration
por: Rossin, Federica, et al.
Publicado: (2021)

Sensitivity of Global Translation to mTOR Inhibition in REN Cells Depends on the Equilibrium between eIF4E and 4E-BP1
por: Grosso, Stefano, et al.
Publicado: (2011)

GNL3L Depletion Destabilizes MDM2 and Induces p53-Dependent G2/M Arrest
por: Meng, Lingjun, et al.
Publicado: (2010)

Binding of sFRP-3 to EGF in the Extra-Cellular Space Affects Proliferation, Differentiation and Morphogenetic Events Regulated by the Two Molecules
por: Scardigli, Raffaella, et al.
Publicado: (2008)

COVID-19 and PIMS—Two Different Entities, but the Same Trigger
por: Meliț, Lorena Elena, et al.
Publicado: (2022)

Characterization of the Skeletal Muscle Secretome Reveals a Role for Extracellular Vesicles and IL1α/IL1β in Restricting Fibro/Adipogenic Progenitor Adipogenesis
por: Vumbaca, Simone, et al.
Publicado: (2021)

Linac4 PIMS
por: Pantelia, Anna
Publicado: (2014)

The role of PIM1/PIM2 kinases in tumors of the male reproductive system
por: Jiménez-García, Manuel Pedro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_qeervcq0bbnvk2vvjq7ejhc1t8