IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1α and PERK signaling

Sophoridinic acid derivatives have received considerable attentions for their potencies in cancer therapy. IMB-6G is a novel N-substituted sophoridinic acid derivative with potent cytotoxicity against tumor cells. In the present study, we explored the antitumor abilities of IMB-6G in human hepatocel...

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Detalles Bibliográficos
Autores principales: Zhang, Na, Bi, Chongwen, Liu, Lu, Dou, Yueying, Tang, Sheng, Pang, Weiqiang, Deng, Hongbin, Song, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029669/
https://www.ncbi.nlm.nih.gov/pubmed/27009865
http://dx.doi.org/10.18632/oncotarget.8184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029669/
https://www.ncbi.nlm.nih.gov/pubmed/27009865
http://dx.doi.org/10.18632/oncotarget.8184

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