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Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis

The conversion of precancerous lesions to full-fledged cancers requires the affected cells to surpass certain rate-limiting steps. We recently showed that activation of HRAS proto-oncogene in urothelial cells of transgenic mice causes simple urothelial hyperplasia (SUH) which is persistent and whose...

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Detalles Bibliográficos
Autores principales: Zhou, Haiping, Wang, Xing, Mo, Lan, Liu, Yan, He, Feng, Zhang, Fenglin, Huang, Kuo-How, Wu, Xue-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029676/
https://www.ncbi.nlm.nih.gov/pubmed/26992222
http://dx.doi.org/10.18632/oncotarget.8114