Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion

The lysyl deacetylase SIRT1 acts as a metabolic sensor in adjusting metabolic imbalance. To explore the role of SIRT1 in tumor-stroma interplay, we designed an in vivo tumor model using SIRT1-transgenic mice. B16F10 mouse melanoma grew more quickly in SIRT1-transgenic mice than in wild-type mice, wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Dong Hoon, Choi, Yong-Joon, Jin, Peng, Yoon, Haejin, Chun, Yang-Sook, Shin, Hyun-Woo, Kim, Ja-Eun, Park, Jong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029678/
https://www.ncbi.nlm.nih.gov/pubmed/26992208
http://dx.doi.org/10.18632/oncotarget.8073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029678/
https://www.ncbi.nlm.nih.gov/pubmed/26992208
http://dx.doi.org/10.18632/oncotarget.8073

Ejemplares similares