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Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion

The lysyl deacetylase SIRT1 acts as a metabolic sensor in adjusting metabolic imbalance. To explore the role of SIRT1 in tumor-stroma interplay, we designed an in vivo tumor model using SIRT1-transgenic mice. B16F10 mouse melanoma grew more quickly in SIRT1-transgenic mice than in wild-type mice, wh...

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Detalles Bibliográficos
Autores principales:	Shin, Dong Hoon, Choi, Yong-Joon, Jin, Peng, Yoon, Haejin, Chun, Yang-Sook, Shin, Hyun-Woo, Kim, Ja-Eun, Park, Jong-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029678/ https://www.ncbi.nlm.nih.gov/pubmed/26992208 http://dx.doi.org/10.18632/oncotarget.8073

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