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Transmembrane adaptor protein PAG1 is a novel tumor suppressor in neuroblastoma

(NB) is the most common extracranial pediatric solid tumor with high mortality rates. The tyrosine kinase c-Src has been known to play an important role in differentiation of NB cells, but the mechanism of c-Src regulation has not been defined. Here, we characterize PAG1 (Cbp, Csk binding protein),...

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Detalles Bibliográficos
Autores principales: Agarwal, Saurabh, Ghosh, Rajib, Chen, Zaowen, Lakoma, Anna, Gunaratne, Preethi H., Kim, Eugene S., Shohet, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029681/
https://www.ncbi.nlm.nih.gov/pubmed/26993602
http://dx.doi.org/10.18632/oncotarget.8116