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cRGD inhibits vasculogenic mimicry formation by down-regulating uPA expression and reducing EMT in ovarian cancer

Vasculogenic minicry (VM), an alternative blood supply modality except to endothelial cells-mediated vascular network, is a potential therapeutic target for ovarian cancer due to VM correlated with poor prognosis in ovarian cancer patients. Accelerated extracellular matrix (ECM) degradation is prere...

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Detalles Bibliográficos
Autores principales: Tang, Jiao, Wang, Jianguo, Fan, Lin, Li, Xiaoxuan, Liu, Na, Luo, Wanxian, Wang, Jihui, Wang, Yifeng, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029683/
https://www.ncbi.nlm.nih.gov/pubmed/26992227
http://dx.doi.org/10.18632/oncotarget.8079